Next-generation Sequencing of Advanced Prostate Cancer Treated with Androgen-deprivation Therapy

BACKGROUND: Androgen-deprivation therapy (ADT) is standard treatment for locally advanced or metastatic prostate cancer (PCa). Many patients develop castration resistance (castration-resistant PCa [CRPC]) after approximately 2–3 yr, with a poor prognosis. The molecular mechanisms underlying CRPC pro...

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Detalhes bibliográficos
Main Authors: Rajan, Prabhakar, Sudbery, Ian M., Villasevil, M. Eugenia M., Mui, Ernest, Fleming, Janis, Davis, Mark, Ahmad, Imran, Edwards, Joanne, Sansom, Owen J., Sims, David, Ponting, Chris P., Heger, Andreas, McMenemin, Rhona M., Pedley, Ian D., Leung, Hing Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2014
Assuntos:
Platinum Priority – Prostate Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062940/
https://ncbi.nlm.nih.gov/pubmed/24054872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2013.08.011
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