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High-Definition Reconstruction of Clonal Composition in Cancer
The extensive genetic heterogeneity of cancers can greatly affect therapy success due to the existence of subclonal mutations conferring resistance. However, the characterization of subclones in mixed-cell populations is computationally challenging due to the short length of sequence reads that are...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Cell Press
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4062932/ https://ncbi.nlm.nih.gov/pubmed/24882004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.04.055 |
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