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Toward a hierarchy of mechanisms in CaMKII-mediated arrhythmia

Calcium/calmodulin-dependent protein kinase II (CaMKII) activity has been shown to contribute to arrhythmogenesis in a remarkably broad range of cardiac pathologies. Several of these involve significant structural and electrophysiologic remodeling, whereas others are due to specific channelopathies,...

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Autori principali: Vincent, Kevin P., McCulloch, Andrew D., Edwards, Andrew G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062880/
https://ncbi.nlm.nih.gov/pubmed/24994983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00110
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