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Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent t-loop formation

We have applied a super-resolution fluorescence imaging method, STochastic Optical Reconstruction Microscopy (STORM), to visualize the structure of functional telomeres and telomeres rendered dysfunctional through removal of shelterin proteins. The STORM images showed that functional telomeres frequ...

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Autors principals: Doksani, Ylli, Wu, John Y., de Lange, Titia, Zhuang, Xiaowei
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062873/
https://ncbi.nlm.nih.gov/pubmed/24120135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.09.048
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