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HIV protein Nef causes dyslipidemia and formation of foam cells in mouse models of atherosclerosis

Patients with HIV are at an increased risk of cardiovascular disease. In this study we investigated the effect of Nef, a secreted HIV protein responsible for the impairment of cholesterol efflux, on the development of atherosclerosis in two animal models. ApoE(−/−) mice fed a high-fat diet and C57BL...

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Bibliografske podrobnosti
Main Authors: Cui, Huanhuan L., Ditiatkovski, Michael, Kesani, Rajitha, Bobryshev, Yuri V., Liu, Yingying, Geyer, Matthias, Mukhamedova, Nigora, Bukrinsky, Michael, Sviridov, Dmitri
Format: Artigo
Jezik:Inglês
Izdano: Federation of American Societies for Experimental Biology 2014
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062825/
https://ncbi.nlm.nih.gov/pubmed/24642731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-246876
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