Vascular characterization of mice with endothelial expression of cytochrome P450 4F2

Cytochrome P450 (CYP) 4A and 4F enzymes metabolize arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE). Although CYP4A-derived 20-HETE is known to have prohypertensive and proangiogenic properties, the effects of CYP4F-derived metabolites are not well characterized. To investigate the role...

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Hlavní autoři: Cheng, Jennifer, Edin, Matthew L., Hoopes, Samantha L., Li, Hong, Bradbury, J. Alyce, Graves, Joan P., DeGraff, Laura M., Lih, Fred B., Garcia, Victor, Shaik, Jafar Sadik B., Tomer, Kenneth B., Flake, Gordon P., Falck, John R., Lee, Craig R., Poloyac, Samuel M., Schwartzman, Michal L., Zeldin, Darryl C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2014
Témata:
Research Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062824/
https://ncbi.nlm.nih.gov/pubmed/24668751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-241927
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