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HIV persistence: Chemokines and their signalling pathways

Latently infected resting CD4+ T cells are the major barrier to curing HIV. We have recently demonstrated that chemokines, which bind to the chemokine receptors CCR7, CXCR3 and CCR6, facilitate efficient HIV nuclear localisation and integration in resting CD4+ T cells, leading to latency. As latentl...

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Detalhes bibliográficos
Main Authors: Evans, Vanessa A., Khoury, Gabriela, Saleh, Suha, Cameron, Paul U., Lewin, Sharon R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062707/
https://ncbi.nlm.nih.gov/pubmed/22749173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cytogfr.2012.05.002
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