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HIV persistence: Chemokines and their signalling pathways

Latently infected resting CD4+ T cells are the major barrier to curing HIV. We have recently demonstrated that chemokines, which bind to the chemokine receptors CCR7, CXCR3 and CCR6, facilitate efficient HIV nuclear localisation and integration in resting CD4+ T cells, leading to latency. As latentl...

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Détails bibliographiques
Auteurs principaux: Evans, Vanessa A., Khoury, Gabriela, Saleh, Suha, Cameron, Paul U., Lewin, Sharon R.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062707/
https://ncbi.nlm.nih.gov/pubmed/22749173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cytogfr.2012.05.002
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