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Murine Notch1 is required for lymphatic vascular morphogenesis during development

BACKGROUND: The transmembrane receptor Notch1 is a critical regulator of arterial differentiation and blood vessel sprouting. Recent evidence shows that functional blockade of Notch1 and its ligand, Dll-4, leads to postnatal lymphatic defects in mice. However, the precise role of the Notch signaling...

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Detalhes bibliográficos
Main Authors: Fatima, Anees, Culver, Austin, Culver, Ford, Liu, Ting, Dietz, William H., Thomson, Benjamin R., Hadjantonakis, Anna-Katerina, Quaggin, Susan E., Kume, Tsutomu
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062592/
https://ncbi.nlm.nih.gov/pubmed/24659232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.24129
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