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PIP(2) regulates psychostimulant behaviors through its interaction with a membrane protein
Phosphatidylinositol (4,5)-bisphosphate (PIP(2)) regulates the function of ion channels and transporters. Here, we demonstrate that PIP(2) directly binds the human dopamine (DA) transporter (hDAT), a key regulator of DA homeostasis and a target of the psychostimulant amphetamine (AMPH). This binding...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4062427/ https://ncbi.nlm.nih.gov/pubmed/24880859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1545 |
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