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Exploiting the Divalent Nature of Isonitriles: a novel Pictet–Spengler Amidination process
An isocyanide-based multicomponent reaction (IMCR) utilized for the rapid assembly of novel, biologically relevant dihydropyrrolo[1,2-a]quinoxalines-amidines is herein presented. Starting from 1-(2-aminophenyl)pyrroles, aldehydes, and isonitriles, the target heterocyclic scaffold is assembled in a o...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4062309/ https://ncbi.nlm.nih.gov/pubmed/24954960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2014.04.043 |
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