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Exploiting the Divalent Nature of Isonitriles: a novel Pictet–Spengler Amidination process

An isocyanide-based multicomponent reaction (IMCR) utilized for the rapid assembly of novel, biologically relevant dihydropyrrolo[1,2-a]quinoxalines-amidines is herein presented. Starting from 1-(2-aminophenyl)pyrroles, aldehydes, and isonitriles, the target heterocyclic scaffold is assembled in a o...

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Bibliografski detalji
Glavni autori: Medda, Federico, Hulme, Christopher
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062309/
https://ncbi.nlm.nih.gov/pubmed/24954960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2014.04.043
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