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Human-specific epigenetic variation in the immunological Leukotriene B4 Receptor (LTB4R/BLT1) implicated in common inflammatory diseases

BACKGROUND: Common human diseases are caused by the complex interplay of genetic susceptibility as well as environmental factors. Due to the environment’s influence on the epigenome, and therefore genome function, as well as conversely the genome’s facilitative effect on the epigenome, analysis of t...

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Autors principals: Wilson, Gareth A, Butcher, Lee M, Foster, Holly R, Feber, Andrew, Roos, Christian, Walter, Lutz, Woszczek, Grzegorz, Beck, Stephan, Bell, Christopher G
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062055/
https://ncbi.nlm.nih.gov/pubmed/24598577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm536
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