Predicting targeted drug combinations based on Pareto optimal patterns of coexpression network connectivity

BACKGROUND: Molecularly targeted drugs promise a safer and more effective treatment modality than conventional chemotherapy for cancer patients. However, tumors are dynamic systems that readily adapt to these agents activating alternative survival pathways as they evolve resistant phenotypes. Combin...

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Detaylı Bibliyografya
Asıl Yazarlar: Penrod, Nadia M, Greene, Casey S, Moore, Jason H
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062052/
https://ncbi.nlm.nih.gov/pubmed/24944582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm550
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