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Influence networks based on coexpression improve drug target discovery for the development of novel cancer therapeutics

BACKGROUND: The demand for novel molecularly targeted drugs will continue to rise as we move forward toward the goal of personalizing cancer treatment to the molecular signature of individual tumors. However, the identification of targets and combinations of targets that can be safely and effectivel...

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Detalhes bibliográficos
Main Authors: Penrod, Nadia M, Moore, Jason H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922430/
https://ncbi.nlm.nih.gov/pubmed/24495353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-8-12
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