The Binding of Antigenic Peptides to HLA-DR Is Influenced by Interactions between Pocket 6 and Pocket 9()

Peptide binding to class II MHC protein is commonly viewed as a combination of discrete anchor residue preferences for pockets 1, 4, 6/7, and 9. However, previous studies have suggested cooperative effects during the peptide binding process. Investigation of the DRB1*0901 binding motif demonstrated...

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Main Authors: James, Eddie A., Moustakas, Antonis K., Bui, John, Nouv, Randi, Papadopoulos, George K., Kwok, William W.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061985/
https://ncbi.nlm.nih.gov/pubmed/19648278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802228
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