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The Microenvironment Matters: Estrogen Deficiency Fuels Cancer Bone Metastases

Factors released during osteoclastic bone resorption enhance disseminated breast cancer cell progression by stimulating invasiveness, growth and a bone-resorptive phenotype in cancer cells. Post-menopausal bone loss may accelerate progression of breast cancer growth in bone, explaining the anti-canc...

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Detalhes bibliográficos
Main Authors: Wright, Laura E., Guise, Theresa A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061908/
https://ncbi.nlm.nih.gov/pubmed/24803577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0576
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