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EFIN: predicting the functional impact of nonsynonymous single nucleotide polymorphisms in human genome

BACKGROUND: Predicting the functional impact of amino acid substitutions (AAS) caused by nonsynonymous single nucleotide polymorphisms (nsSNPs) is becoming increasingly important as more and more novel variants are being discovered. Bioinformatics analysis is essential to predict potentially causal...

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Detalhes bibliográficos
Main Authors: Zeng, Shuai, Yang, Jing, Chung, Brian Hon-Yin, Lau, Yu Lung, Yang, Wanling
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061446/
https://ncbi.nlm.nih.gov/pubmed/24916671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-455
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