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Bayesian Hidden Markov Models to Identify RNA-Protein Interaction Sites in PAR-CLIP

The photoactivatable ribonucleoside enhanced cross-linking immunoprecipitation (PAR-CLIP) has been increasingly used for the global mapping of RNA-protein interaction sites. There are two key features of the PAR-CLIP experiments: The sequence read tags are likely to form an enriched peak around each...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yun, Jonghyun, Wang, Tao, Xiao, Guanghua
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061157/
https://ncbi.nlm.nih.gov/pubmed/24571656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12147
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