A Stable and Reproducible Human Blood-Brain Barrier Model Derived from Hematopoietic Stem Cells

The human blood brain barrier (BBB) is a selective barrier formed by human brain endothelial cells (hBECs), which is important to ensure adequate neuronal function and protect the central nervous system (CNS) from disease. The development of human in vitro BBB models is thus of utmost importance for...

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Main Authors: Cecchelli, Romeo, Aday, Sezin, Sevin, Emmanuel, Almeida, Catarina, Culot, Maxime, Dehouck, Lucie, Coisne, Caroline, Engelhardt, Britta, Dehouck, Marie-Pierre, Ferreira, Lino
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061029/
https://ncbi.nlm.nih.gov/pubmed/24936790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099733
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