A Stable and Reproducible Human Blood-Brain Barrier Model Derived from Hematopoietic Stem Cells

The human blood brain barrier (BBB) is a selective barrier formed by human brain endothelial cells (hBECs), which is important to ensure adequate neuronal function and protect the central nervous system (CNS) from disease. The development of human in vitro BBB models is thus of utmost importance for...

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Main Authors: Cecchelli, Romeo, Aday, Sezin, Sevin, Emmanuel, Almeida, Catarina, Culot, Maxime, Dehouck, Lucie, Coisne, Caroline, Engelhardt, Britta, Dehouck, Marie-Pierre, Ferreira, Lino
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061029/
https://ncbi.nlm.nih.gov/pubmed/24936790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099733
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