Solution Structure of the 2A Protease from a Common Cold Agent, Human Rhinovirus C2, Strain W12

Human rhinovirus strains differ greatly in their virulence, and this has been correlated with the differing substrate specificity of the respective 2A protease (2A(pro)). Rhinoviruses use their 2A(pro) to cleave a spectrum of cellular proteins important to virus replication and anti-host activities....

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Hauptverfasser: Lee, Woonghee, Watters, Kelly E., Troupis, Andrew T., Reinen, Nichole M., Suchy, Fabian P., Moyer, Kylie L., Frederick, Ronnie O., Tonelli, Marco, Aceti, David J., Palmenberg, Ann C., Markley, John L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061012/
https://ncbi.nlm.nih.gov/pubmed/24937088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097198
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