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Epigenetic analysis of HIV-1 proviral genomes from infected individuals: Predominance of unmethylated CpG’s
Efforts to cure HIV-1 infections aim at eliminating proviral DNA. Integrated DNA from various viruses often becomes methylated de novo and transcriptionally inactivated. We therefore investigated CpG methylation profiles of 55 of 94 CpG’s (58.5%) in HIV-1 proviral genomes including ten CpG’s in each...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4060985/ https://ncbi.nlm.nih.gov/pubmed/24418551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.11.013 |
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