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MR Molecular Imaging of Prostate Cancer with a Peptide Targeted Contrast Agent in a Mouse Orthotopic Prostate Cancer Model

PURPOSE: To study the effectiveness of a peptide targeted nanoglobular Gd-DOTA complexes for MR molecular imaging of prostate cancer in a mouse orthotopic PC-3 prostate cancer model. METHODS: A CLT1 (CGLIIQKNEC) peptide targeted generation 2 nanoglobular Gd-DOTA monoamide conjugate [CLT1-G2-(Gd-DOTA...

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Bibliographic Details
Main Authors: Tan, Mingqian, Burden-Gulley, Susan M., Li, Wen, Wu, Xueming, Lindner, Daniel, Brady-Kalnay, Susann M., Gulani, Vikas, Lu, Zheng-Rong
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060974/
https://ncbi.nlm.nih.gov/pubmed/22139536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-011-0635-y
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