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Synthesis and Evaluation of a Targeted Nanoglobular Dual-Modal Imaging Agent for MR Imaging and Image-Guided Surgery of Prostate Cancer

PURPOSE: To synthesize and evaluate a peptide targeted nanoglobular dual modal imaging agent specific to a cancer biomarker in tumor stroma for MRI and fluorescence visualization of prostate tumor in image-guided surgery. METHODS: A peptide (CGLIIQKNEC, CLT1) targeted generation 2 nanoglobular (poly...

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Detalhes bibliográficos
Main Authors: Tan, Mingqian, Ye, Zhen, Lindner, Daniel, Brady-Kalnay, Susann M., Lu, Zheng-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895102/
https://ncbi.nlm.nih.gov/pubmed/23471641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1008-5
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