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Synthesis and evaluation of a nanoglobular dendrimer 5-aminosalicylic acid conjugate with a hydrolyzable Schiff base spacer for treating retinal degeneration

Biocompatible dendrimers with well-defined nanosizes are increasingly being used as carriers for drug delivery. 5-Aminosalicylic acid (5-ASA) is an FDA approved therapeutic agent recently found effective in treating retinal degeneration of animal models. Here, a water-soluble dendrimer conjugate of...

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Detalhes bibliográficos
Main Authors: Wu, Xueming, Yu, Guanping, Luo, Chengcai, Maeda, Akiko, Zhang, Ning, Sun, Da, Zhou, Zhuxian, Puntel, Anthony, Palczewski, Krzysztof, Lu, Zheng-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060971/
https://ncbi.nlm.nih.gov/pubmed/24350906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn4054107
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