Synthesis, Characterization, and in Vitro Evaluation of a New TSPO-Selective Bifunctional Chelate Ligand

[Image: see text] The 18-kDa translocator protein (TSPO) is overexpressed in many types of cancers and is also abundant in activated microglial cells occurring in inflammatory neurodegenerative diseases. Thus, TSPO has become an extremely attractive subcellular target not only for imaging disease st...

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Hauptverfasser: Denora, Nunzio, Margiotta, Nicola, Laquintana, Valentino, Lopedota, Angela, Cutrignelli, Annalisa, Losacco, Maurizio, Franco, Massimo, Natile, Giovanni
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060941/
https://ncbi.nlm.nih.gov/pubmed/24944744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml5000788
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