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Synthesis, Characterization, and in Vitro Evaluation of a New TSPO-Selective Bifunctional Chelate Ligand

[Image: see text] The 18-kDa translocator protein (TSPO) is overexpressed in many types of cancers and is also abundant in activated microglial cells occurring in inflammatory neurodegenerative diseases. Thus, TSPO has become an extremely attractive subcellular target not only for imaging disease st...

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Main Authors: Denora, Nunzio, Margiotta, Nicola, Laquintana, Valentino, Lopedota, Angela, Cutrignelli, Annalisa, Losacco, Maurizio, Franco, Massimo, Natile, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2014
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060941/
https://ncbi.nlm.nih.gov/pubmed/24944744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml5000788
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