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Structure of the branched intermediate in protein splicing

Inteins are autoprocessing domains that cut themselves out of host proteins in a traceless manner. This process, known as protein splicing, involves multiple chemical steps that must be coordinated to ensure fidelity in the process. The committed step in splicing involves attack of a conserved Asn s...

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Библиографические подробности
Главные авторы: Liu, Zhihua, Frutos, Silvia, Bick, Matthew J., Vila-Perelló, Miquel, Debelouchina, Galia T., Darst, Seth A., Muir, Tom W.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060664/
https://ncbi.nlm.nih.gov/pubmed/24778214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402942111
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