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Coliphage HK022 Nun protein inhibits RNA polymerase translocation

The Nun protein of coliphage HK022 arrests RNA polymerase (RNAP) in vivo and in vitro at pause sites distal to phage λ N-Utilization (nut) site RNA sequences. We tested the activity of Nun on ternary elongation complexes (TECs) assembled with templates lacking the λ nut sequence. We report that Nun...

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Autori principali: Vitiello, Christal L., Kireeva, Maria L., Lubkowska, Lucyna, Kashlev, Mikhail, Gottesman, Max
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060646/
https://ncbi.nlm.nih.gov/pubmed/24853501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319740111
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