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Distinctive Roles for OAS and PKR in the in Vivo Anti-Viral Effect of an Adenoviral Vector Expressing Murine IFN-β()

To evaluate the anti-herpes simplex virus type 1 (HSV-1) mechanisms of murine IFN-β in ocular infection mice were transduced with an adenoviral vector expressing murine IFN-β (Ad:IFN-β). Ocular transduction with Ad:IFN-β resulted in enhanced survival following infection with HSV-1. The protective ef...

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Bibliografiske detaljer
Main Authors: Al-khatib, Khaldun, Williams, Bryan R.G., Silverman, Robert H., Halford, William, Carr, Daniel J.J.
Format: Artigo
Sprog:Inglês
Udgivet: 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060620/
https://ncbi.nlm.nih.gov/pubmed/15100308
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