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Depletion of the Trypanosome Pumilio Domain Protein PUF2 or of Some Other Essential Proteins Causes Transcriptome Changes Related to Coding Region Length

Pumilio domain RNA-binding proteins are known mainly as posttranscriptional repressors of gene expression that reduce mRNA translation and stability. Trypanosoma brucei has 11 PUF proteins. We show here that PUF2 is in the cytosol, with roughly the same number of molecules per cell as there are mRNA...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jha, Bhaskar Anand, Fadda, Abeer, Merce, Clementine, Mugo, Elisha, Droll, Dorothea, Clayton, Christine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060476/
https://ncbi.nlm.nih.gov/pubmed/24681684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00018-14
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