Modulation of Antigen-Specific T-Cells as Immune Therapy for Chronic Infectious Diseases and Cancer

T-cell responses are induced by antigen presenting cells (APC) and signals from the microenvironment. Antigen persistence and inflammatory microenvironments in chronic infections and cancer can induce a tolerant state in T-cells resulting in hyporesponsiveness, loss of effector function, and weak bi...

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Bibliografiska uppgifter
Huvudupphovsmän: Li, Suling, Symonds, Alistair L. J., Miao, Tizong, Sanderson, Ian, Wang, Ping
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2014
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060297/
https://ncbi.nlm.nih.gov/pubmed/24987395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00293
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