Single-step Antibody-based Affinity Cryo-Electron Microscopy for Imaging and Structural Analysis of Macromolecular Assemblies

Single particle cryo-electron microscopy (cryo-EM) is an emerging powerful tool for structural studies of macromolecular assemblies (i.e., protein complexes and viruses). Although single particle cryo-EM requires less concentrated and smaller amounts of samples than X-ray crystallography, it remains...

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Detalhes bibliográficos
Main Authors: Yu, Guimei, Vago, Frank, Zhang, Dongsheng, Snyder, Jonathan E., Yan, Rui, Zhang, Ci, Benjamin, Christopher, Jiang, Xi, Kuhn, Richard J., Serwer, Philip, Thompson, David H., Jiang, Wen
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060259/
https://ncbi.nlm.nih.gov/pubmed/24780590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2014.04.006
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