Adenosine A(2A )receptors promote collagen production by a Fli1- and CTGF-mediated mechanism

INTRODUCTION: Adenosine, acting through the A(2A )receptor, promotes tissue matrix production in the skin and the liver and induces the development of dermal fibrosis and cirrhosis in murine models. Since expression of A(2A )receptors is increased in scleroderma fibroblasts, we examined the mechanis...

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Bibliographic Details
Main Authors: Chan, Edwin SL, Liu, Hailing, Fernandez, Patricia, Luna, Alex, Perez-Aso, Miguel, Bujor, Andreea M, Trojanowska, Maria, Cronstein, Bruce N
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060252/
https://ncbi.nlm.nih.gov/pubmed/23663495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4229
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