CD4(+)CD25(+/high)CD127(low/-) regulatory T cells are enriched in rheumatoid arthritis and osteoarthritis joints—analysis of frequency and phenotype in synovial membrane, synovial fluid and peripheral blood

INTRODUCTION: CD4(+)CD25(+/high)CD127(low/-) regulatory T cells (Tregs) play a crucial role in maintaining peripheral tolerance. Data about the frequency of Tregs in rheumatoid arthritis (RA) are contradictory and based on the analysis of peripheral blood (PB) and synovial fluid (SF). Because Tregs...

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Bibliografische gegevens
Hoofdauteurs: Moradi, Babak, Schnatzer, Philipp, Hagmann, Sébastien, Rosshirt, Nils, Gotterbarm, Tobias, Kretzer, Jan Philippe, Thomsen, Marc, Lorenz, Hanns-Martin, Zeifang, Felix, Tretter, Theresa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2014
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060198/
https://ncbi.nlm.nih.gov/pubmed/24742142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4545
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