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CD4(+)CD25(+/high)CD127(low/-) regulatory T cells are enriched in rheumatoid arthritis and osteoarthritis joints—analysis of frequency and phenotype in synovial membrane, synovial fluid and peripheral blood

INTRODUCTION: CD4(+)CD25(+/high)CD127(low/-) regulatory T cells (Tregs) play a crucial role in maintaining peripheral tolerance. Data about the frequency of Tregs in rheumatoid arthritis (RA) are contradictory and based on the analysis of peripheral blood (PB) and synovial fluid (SF). Because Tregs...

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Bibliografiske detaljer
Main Authors: Moradi, Babak, Schnatzer, Philipp, Hagmann, Sébastien, Rosshirt, Nils, Gotterbarm, Tobias, Kretzer, Jan Philippe, Thomsen, Marc, Lorenz, Hanns-Martin, Zeifang, Felix, Tretter, Theresa
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060198/
https://ncbi.nlm.nih.gov/pubmed/24742142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4545
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