Mesangial cell α(v)β(8)-integrin regulates glomerular capillary integrity and repair

α(v)β(8)-Integrin is most abundantly expressed in the kidney, brain, and female reproductive organs, and its cognate ligand is latent transforming growth factor (LTGF)-β. Kidney α(v)β(8)-integrin localizes to mesangial cells, and global β(8)-integrin gene (Itgb8) deletion results in embryonic lethal...

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Hauptverfasser: Lakhe-Reddy, Sujata, Li, Vincent, Arnold, Thomas D., Khan, Shenaz, Schelling, Jeffrey R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2014
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059974/
https://ncbi.nlm.nih.gov/pubmed/24740792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00624.2013
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