Mesangial Cell Integrin αvβ8 Provides Glomerular Endothelial Cell Cytoprotection by Sequestering TGF-β and Regulating PECAM-1

Integrins are heterodimeric receptors that regulate cell adhesion, migration, and apoptosis. Integrin αvβ8 is most abundantly expressed in kidney and brain, and its major ligand is latent transforming growth factor-β (TGF-β). Kidney αvβ8 localizes to mesangial cells, which appose glomerular endothel...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Khan, Shenaz, Lakhe-Reddy, Sujata, McCarty, Joseph H., Sorenson, Christine M., Sheibani, Nader, Reichardt, Louis F., Kim, Jane H., Wang, Bingcheng, Sedor, John R., Schelling, Jeffrey R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2011
Konular:
Regular Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070557/
https://ncbi.nlm.nih.gov/pubmed/21281793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.10.031
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller