Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity

The emerging role of the transient receptor potential cation channel isotype 6 (TRPC6) as a central contributor to various pathological processes affecting podocytes has generated interest in the development of therapeutics to modulate its function. Recent insights into the regulation of TRPC6 have...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hall, Gentzon, Rowell, Janelle, Farinelli, Federica, Gbadegesin, Rasheed A., Lavin, Peter, Wu, Guanghong, Homstad, Alison, Malone, Andrew, Lindsey, Thomas, Jiang, Ruiji, Spurney, Robert, Tomaselli, Gordon F., Kass, David A., Winn, Michelle P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2014
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059973/
https://ncbi.nlm.nih.gov/pubmed/24740790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00212.2013
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