Synaptic recruitment of gephyrin regulates surface GABA(A) receptor dynamics for the expression of inhibitory LTP

Postsynaptic long-term potentiation of inhibition (iLTP) can rely on increased GABA(A) receptors (GABA(A)Rs) at synapses by promoted exocytosis. However, the molecular mechanisms that enhance the clustering of postsynaptic GABA(A)Rs during iLTP remain obscure. Here we demonstrate that during chemica...

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Autors principals: Petrini, Enrica Maria, Ravasenga, Tiziana, Hausrat, Torben J., Iurilli, Giuliano, Olcese, Umberto, Racine, Victor, Sibarita, Jean-Baptiste, Jacob, Tija C., Moss, Stephen J., Benfenati, Fabio, Medini, Paolo, Kneussel, Matthias, Barberis, Andrea
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059940/
https://ncbi.nlm.nih.gov/pubmed/24894704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4921
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