Synaptic recruitment of gephyrin regulates surface GABA(A) receptor dynamics for the expression of inhibitory LTP

Postsynaptic long-term potentiation of inhibition (iLTP) can rely on increased GABA(A) receptors (GABA(A)Rs) at synapses by promoted exocytosis. However, the molecular mechanisms that enhance the clustering of postsynaptic GABA(A)Rs during iLTP remain obscure. Here we demonstrate that during chemica...

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Hauptverfasser: Petrini, Enrica Maria, Ravasenga, Tiziana, Hausrat, Torben J., Iurilli, Giuliano, Olcese, Umberto, Racine, Victor, Sibarita, Jean-Baptiste, Jacob, Tija C., Moss, Stephen J., Benfenati, Fabio, Medini, Paolo, Kneussel, Matthias, Barberis, Andrea
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059940/
https://ncbi.nlm.nih.gov/pubmed/24894704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4921
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