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Complement yourself: transcomplementation rescues partially folded mutant proteins

Cystic fibrosis (CF) is an autosomal disease associated with malfunction in fluid and electrolyte transport across several mucosal membranes. The most common mutation in CF is an in-frame three-base pair deletion that removes a phenylalanine at position 508 in the first nucleotide-binding domain of...

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Bibliografski detalji
Glavni autori: Cebotaru, Liudmila, Guggino, William B.
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059760/
https://ncbi.nlm.nih.gov/pubmed/24949105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-014-0137-3
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