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Relative Hypo- and Hypercortisolism Are Both Associated with Depression and Lower Quality of Life in Bipolar Disorder: A Cross-Sectional Study

BACKGROUND: Depression in unipolar and bipolar disorders is associated with hypothalamic-pituitary-adrenal-axis (HPA-axis) hyperactivity. Also, unipolar disorder has recently been shown to exhibit HPA-axis hypoactivity. We studied for the first time how HPA-axis hypo- and hyperactivity relate to dep...

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Autores principales: Maripuu, Martin, Wikgren, Mikael, Karling, Pontus, Adolfsson, Rolf, Norrback, Karl-Fredrik
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059634/
https://ncbi.nlm.nih.gov/pubmed/24932586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098682
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