Relevance of liver failure for anti-infective agents: from pharmacokinetic alterations to dosage adjustments

The liver is a complex organ with great ability to influence drug pharmacokinetics (PK). Due to its wide array of function, its impairment has the potential to affect bioavailability, enterohepatic circulation, drug distribution, metabolism, clearance, and biliary elimination. These alterations diff...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Büdingen, Fiona V., Gonzalez, Daniel, Tucker, Amelia N., Derendorf, Hartmut
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: SAGE Publications 2014
Konular:
Reviews
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059611/
https://ncbi.nlm.nih.gov/pubmed/24949199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2049936113519089
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