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Macromolecular DCE-MRI detects reduced vascular permeability in a prostate cancer bone metastasis model following anti-PDGFR therapy, indicating a drop in VEGFR activation
The anti-vascular function of platelet-derived growth factor receptor (PDGFR) inhibitor imatinib combined with paclitaxel has been demonstrated by invasive immunohistochemistry. The purpose of this study was 1. to noninvasively monitor the response to anti-PDGFR treatment and 2. to understand the un...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4059608/ https://ncbi.nlm.nih.gov/pubmed/18816866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.21727 |
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