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Macromolecular DCE-MRI detects reduced vascular permeability in a prostate cancer bone metastasis model following anti-PDGFR therapy, indicating a drop in VEGFR activation

The anti-vascular function of platelet-derived growth factor receptor (PDGFR) inhibitor imatinib combined with paclitaxel has been demonstrated by invasive immunohistochemistry. The purpose of this study was 1. to noninvasively monitor the response to anti-PDGFR treatment and 2. to understand the un...

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Detalhes bibliográficos
Main Authors: Dafni, Hagit, Kim, Sun-Jin, Bankson, James A, Sankaranarayanapillai, Madhuri, Ronen, Sabrina M
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059608/
https://ncbi.nlm.nih.gov/pubmed/18816866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.21727
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