The effect of the TLR9 ligand CpG-oligodeoxynucleotide on the protective immune response to alcelaphine herpesvirus-1-mediated malignant catarrhal fever in cattle

We wished to determine the effect of of CpG ODN adjuvant on the magnitude and duration of protective immunity against alcelaphine herpesvirus-1 (AlHV-1) malignant catarrhal fever (MCF), a fatal lymphoproliferative disease of cattle. Immunity was associated with a mucosal barrier of virus-neutralisin...

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Detalhes bibliográficos
Main Authors: Parameswaran, Nevi, Russell, George C, Bartley, Kathryn, Grant, Dawn M, Deane, David, Todd, Helen, Dagleish, Mark P, Haig, David M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059458/
https://ncbi.nlm.nih.gov/pubmed/24886334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9716-45-59
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