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The A2 gene of alcelaphine herpesvirus-1 is a transcriptional regulator affecting cytotoxicity in virus-infected T cells but is not required for malignant catarrhal fever induction in rabbits

Alcelaphine herpesvirus-1 (AlHV-1) causes malignant catarrhal fever (MCF). The A2 gene of AlHV-1 is a member of the bZIP transcription factor family. We wished to determine whether A2 is a virulence gene or not and whether it is involved in pathogenesis by interference with host transcription pathwa...

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Detalhes bibliográficos
Publicado no:Virus Res
Main Authors: Parameswaran, Nevi, Dewals, Benjamin G., Giles, Tom C., Deppmann, Christopher, Blythe, Martin, Vanderplasschen, Alain, Emes, Richard D., Haig, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441327/
https://ncbi.nlm.nih.gov/pubmed/24732177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2014.04.003
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