Reduced expression of PinX1 correlates to progressive features in patients with prostate cancer

BACKGROUND: Pin2/TRF1 binding protein X1 (PinX1) has been identified as an endogenous telomerase inhibitor and a major haploinsufficient tumor suppressor gene. Increasing evidence suggests that reduced expression of PinX1 plays a key role in tumorigenesis. However, the PinX1 expression status and it...

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Autores principales: Shi, Rong, Zhao, Zhen, Zhou, Hui, Wei, Min, Ma, Wen-Li, Zhou, Jue-Yu, Tan, Wan-Long
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Primary Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059453/
https://ncbi.nlm.nih.gov/pubmed/24936151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-14-46
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