MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells

Despite marked advances in breast cancer therapy, basal-like breast cancer (BBC), an aggressive subtype of breast cancer usually lacking estrogen and progesterone receptors, remains difficult to treat. In this study, we report the identification of MELK as a novel oncogenic kinase from an in vivo tu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Yubao, Lee, Young-Mi, Baitsch, Lukas, Huang, Alan, Xiang, Yi, Tong, Haoxuan, Lako, Ana, Von, Thanh, Choi, Christine, Lim, Elgene, Min, Junxia, Li, Li, Stegmeier, Frank, Schlegel, Robert, Eck, Michael J, Gray, Nathanael S, Mitchison, Timothy J, Zhao, Jean J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2014
Pynciau:
Cell Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059381/
https://ncbi.nlm.nih.gov/pubmed/24844244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01763
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