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Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival
The protein kinase maternal and embryonic leucine zipper kinase (MELK) is critical for mitotic progression of cancer cells; however, its mechanisms of action remain largely unknown. By combined approaches of immunoprecipitation/mass spectrometry and peptide library profiling, we identified the eukar...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5024598/ https://ncbi.nlm.nih.gov/pubmed/27528663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606862113 |
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